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Using Naturalistic Vehicle-Based Data to Predict Distraction and Environmental Demand
This research utilized vehicle-based measures from a naturalistic driving dataset to detect distraction as indicated by long off-path glances (≥ 2 s) and whether the driver was engaged in a secondary (non-driving) task or not...
Published by: IGI Global
Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes
Uffe Søholm, Melanie Broadley, Natalie Zaremba, Patrick Divilly, Giesje Nefs, Jill Carlton, Julia K Mader, Petra Martina Baumann, Mikel Gomes, Gilberte Martine-Edith, Daniel J Pollard, Dajana Rath, Simon Heller, Ulrik Pedersen-Bjergaard, Rory J McCrimmon, Eric Renard, Mark Evans, Bastiaan de Galan, Thomas Forkmann, Stephanie A Amiel, Christel Hendrieckx, Jane Speight, Pratik Choudhary, Frans Pouwer
Apr 17, 2023
Introduction
The aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS) application (app): a novel tool designed to assess...
Humans Diabetes mellitus Type 1 Diabetes mellitus Type 2 Hypoglycemia Insulin Reproducibility of Results Psychometrics Adult Aged Middle Aged Benchmarking Mobile Applications Smartphone Surveys and Questionnaires
Published by: PLOS ONE
Managing North-South Research Collaboration Projects During the COVID-19 Pandemic
Researchers from the Global North and South have collaborated for decades to conduct cutting-edge interdisciplinary research. The tools they used to manage their research projects remained virtually unchanged until the COVID-19...
Published by: IGI Global
Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning.
William J Scotton, Cameron Shand, Emily Todd, Martina Bocchetta, David M Cash, Lawren VandeVrede, Hilary Heuer, 4RTNI Consortium PROSPECT Consortium, Alexandra L Young, Neil Oxtoby, Daniel C Alexander, James B Rowe, Huw R Morris, Adam L Boxer, Jonathan D Rohrer, Peter A Wijeratne
Apr 17, 2023
To better understand the pathological and phenotypic heterogeneity of progressive supranuclear palsy and the links between the two, we applied a novel unsupervised machine learning algorithm (Subtype and Stage Inference) to the...
Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools.
Dorota Zawada, Jessica Kornherr, Anna B Meier, Gianluca Santamaria, Tatjana Dorn, Monika Nowak-Imialek, Daniel Ortmann, Fangfang Zhang, Mark Lachmann, Martina Dreßen, Mariaestela Ortiz, Victoria L Mascetti, Stephen C Harmer, Muriel Nobles, Andrew Tinker, Maria Teresa De Angelis, Roger A Pedersen, Phillip Grote, Karl-Ludwig Laugwitz, Alessandra Moretti, Alexander Goedel
Apr 17, 2023
Cardiogenesis relies on the precise spatiotemporal coordination of multiple progenitor populations. Understanding the specification and differentiation of these distinct progenitor pools during human embryonic development is...
Myocardium Heart Myocytes Cardiac Pluripotent Stem Cells Animals Humans Mice Tretinoin Cell Differentiation
Published by: Nature Communications
Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants.
George W Carnell, Martina Billmeier, Sneha Vishwanath, Maria Suau Sans, Hannah Wein, Charlotte L George, Patrick Neckermann, Joanne Marie M Del Rosario, Alexander T Sampson, Sebastian Einhauser, Ernest T Aguinam, Matteo Ferrari, Paul Tonks, Angalee Nadesalingam, Anja Schütz, Chloe Qingzhou Huang, David A Wells, Minna Paloniemi, Ingo Jordan, Diego Cantoni, David Peterhoff, Benedikt Asbach, Volker Sandig, Nigel Temperton, Rebecca Kinsley, Ralf Wagner, Jonathan L Heeney
Apr 12, 2023
The accelerated development of the first generation COVID-19 vaccines has saved millions of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The most successful vaccine candidates have used the...
neutralising antibodies receptor binding domain (RBD) SARS-CoV-2 antibody pseudotype neutralisation glycan masking Humans Polysaccharides Epitopes Antibodies Neutralizing covid-19 SARS-CoV-2 COVID-19 Vaccines
Published by: Frontiers in immunology
Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort
Kiran Samra, Amy M MacDougall, Arabella Bouzigues, Martina Bocchetta, David M Cash, Caroline V Greaves, Rhian S Convery, Chris Hardy, John C van Swieten, Harro Seelaar, Lize C Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jason D Warren, Jonathan D Rohrer, Lucy L Russell, Genetic Frontotemporal dementia Initiative (GENFI)
Apr 17, 2023
Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia
Martina Bocchetta, Emily G Todd, Arabella Bouzigues, David M Cash, Jennifer M Nicholas, Rhian S Convery, Lucy L Russell, David L Thomas, Ian B Malone, Juan Eugenio Iglesias, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris R Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D Rohrer, Genetic Frontotemporal dementia Initiative (GENFI)
Apr 17, 2023